Applying meta-analysis methods in liver failure diagnosis and treatment


Kobrinsky B. Molodchenkov A. Blagosklonov N.


The article considers the principles form the basis of various meta-analysis methods and the main differences of tools for their application. It presents and discusses clinical variants of liver failure and their description in literature of various countries and regions of the world (Russia, Asia, Europe and North America). The authors propose the application of a set-theoretic model, the attributes of which should take into account the features of the character and course of the disease in the different nature of the disease and at different periods of its progress. The obtained data will find use in a subsequent meta-analysis. This stage is the main, it formes subgroups of patients on the similarity of clinical implications and the results of applying different treatment regimens. Choosing the meta-analysis method to estimate the world literature data, this approach will allow offering the most appropriate methods of treatment of the disease in a particular patient depending on the nature of relevant changes in the diagnosis of a certain form of hepatic insufficiency. It will provide a transition (by analogy) to the directed use of certain medical means.

External links

DOI: 10.15827/0236-235X.120.745-753

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Reference link

B. A. Kobrinsky, A. I. Molodchenkov, N. A. Blagosklonov, A. V. Lukin. Applying meta-analysis methods in liver failure diagnosis and treatment // Software & Systems. 2017. Vol. 30, № 4, pp. 745–753.