The transition to personalized medicine in practical terms should combine the solution of the genomics problems as the basis for possible diseases and phenotypic manifestations that are markers and early signs of emerging pathological changes. Most diseases have their first principles in childhood. Therefore, in all age groups, it is necessary to monitor the minimum deviations and their dynamics, use mobile devices for this purpose and accumulate the received data. Processing big data (Big Data) will provide more informative information. On this basis it will be possible to identify analogs for targeted therapy in similar variants of diseases in large databases of publications on the problem of interest.
DOI: 10.21508/1027–4065–2017–62–5–16–20
Download PDF at the Russian Bulletin of Perinatology and Pediatrics journal (in Russian): https://www.ped-perinatology.ru/jour/article/view/545/532
Kobrinskii B. A. Personalized medicine: genome, e-health and intelligent systems. Part 1. Genomics and monitoring of clinical data. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2017;62(5):16-20. (In Russ.)