The paper presents a systematic approach to modeling multilevel regulatory mechanisms of cell growth in multicellular organisms. It has been shown that the interaction of cell populations forms a structure similar to a hypercycle, with feedback loops and adaptive properties. A mathematical model of a cellular hypercycle is proposed, demonstrating the ability of this system to self-organize and recover from external influences.
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Dontsov V. I., Krut'ko V. N. System analysis and modeling of hierarchical regulatory mechanisms of cell growth // Proceeding of the Institute for Systems Analysis of the Russian Academy of Science, 2025, volume 75, № 3, pp. 105–111.